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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGR All Species: 41.82
Human Site: Y459 Identified Species: 92
UniProt: P09769 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09769 NP_001036194.1 529 59479 Y459 I T K G R I P Y P G M N K R E
Chimpanzee Pan troglodytes XP_001158656 541 61057 Y471 V T K G R V P Y P G M N N R E
Rhesus Macaque Macaca mulatta XP_001111657 529 59467 Y459 I T K G R I P Y P G M S K R E
Dog Lupus familis XP_544467 527 59333 Y457 I S K G R V P Y P G M N N R E
Cat Felis silvestris
Mouse Mus musculus P14234 517 58849 Y447 I T K G R V P Y P G M N N R E
Rat Rattus norvegicus Q62844 537 60683 Y467 V T K G R V P Y P G M N N R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521245 533 59723 Y463 I S K G R V P Y P G M N N R E
Chicken Gallus gallus Q02977 536 59984 Y466 V T K G R V P Y P G M N N R E
Frog Xenopus laevis P13406 537 60828 Y467 V T K G R V P Y P G M N N R E
Zebra Danio Brachydanio rerio NP_997946 525 59137 Y455 I T K G R V P Y P G M N N R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9J3 517 59051 Y447 V T Y G R I P Y P G M T N A E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.9 97.5 89 N.A. 84.5 69.4 N.A. 76.1 71.8 69.2 70.8 N.A. 54.2 N.A. N.A. N.A.
Protein Similarity: 100 78.9 98.4 93.1 N.A. 89.7 79.1 N.A. 84.9 82 78.4 82.6 N.A. 67.6 N.A. N.A. N.A.
P-Site Identity: 100 80 93.3 80 N.A. 86.6 80 N.A. 80 80 80 86.6 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 93.3 N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 93.3 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 100 0 0 0 0 0 100 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 55 0 0 0 0 28 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 91 0 0 0 0 0 0 0 0 0 19 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 82 82 0 0 % N
% Pro: 0 0 0 0 0 0 100 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 100 0 0 0 0 0 0 0 0 91 0 % R
% Ser: 0 19 0 0 0 0 0 0 0 0 0 10 0 0 0 % S
% Thr: 0 82 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 46 0 0 0 0 73 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _